�Takeda Pharmaceutical Company Limited (TOKYO:4502) and Affymax, Inc. (Nasdaq:AFFY) today announced their agreement to suspend co-development of Hematide� to treat chemotherapy-induced anemia and to focus all development efforts for Hematide� on the treatment of chronic kidney disease related anemia. Takeda and Affymax continue to be encouraged by the potential of bringing Hematide, a commodious, once monthly treatment alternative, to the millions of chronic kidney disease patients suffering from anemia and believe this represents a significant opportunity for the two companies.
Takeda has been conducting Phase I clinical studies of Hematide� for the treatment of chemotherapy-induced anemia in the U.S. and Japan. However, the companies have decided to suspend development of Hematide in oncology and not to enroll newfangled patients in the on-going Phase I clinical trial of the product in chemotherapy-induced anaemia given the uncertain regulative landscapes for
Thursday 4 September 2008
Monday 25 August 2008
Poetry reading is the new rock'n'roll
The mention of poetry readings has often been sufficiency to pull in a room before the reader has even had chance to clear his or her throat. Now, the Myspace generation is taking its poetry to stages at rock festivals that would normally be the preserve of seasoned performers such as John Cooper Clarke or John Hegley.
One of the rising stars is 22-year-old Laura Dockrill, a former Brit School prot�g�e. She has Glastonbury, Latitude and Summer Sundae festivals under her belt already and has supported Adele, Kate Nash and Martha Wainwright on hitch. Her poems posted on the Myspace website birth been listened to over 300,000 times. This weekend Ms Dockrill volition be playing in figurehead of hundreds of citizenry at the Reading Festival.
"I'm playing the Alternative Stage at Reading, which can be a minute worrying as it is known as having quite a a ill-famed rock crowd," said Dockrill. "I make had strong times before � regular with Kate Nash's hearing. I've had people shout out out: 'I didn't issue forth here to hear tap!' I wrote my first verse form at the age of six, simply I never really thought I would turn out doing it as a full-time career."
The poet, who has signed a major publication deal with HarperCollins for her first base book Mistakes in the Background, believes that performance poetry or spoken word of honor, as it is also called, is about to break into the mainstream.
"I definitely think it's release to get hold of off in the side by side few days. There's so many good artists out there like Scroobius Pip and Aisle16. They are really exciting."
Last week the final of the third annual Summer Poetry Slam competition took place at the Roundhouse in London. Poets cured between 13 and 21 performed in front of hundreds of other teenagers and a panel of judges, competing to be crowned Summer Slam poetry champion 2008.
BBC Radio, which features Bespoken Word on Radio 4, has added another slot in its roster for poetry on Colin Murray's Radio 1 show.
Graham Frost, the jehovah of Bespoken Word, aforesaid that a new generation had developed: "There is a new type of entertainment which is packing people in to the performances. It's performance verse with selfsame strong ethics. There's an empowering nature where offspring people from all different backgrounds are addressing issues such as knife law-breaking, media pressure, the credit crunch, suicides. We're now seeing brigham Young people using their brains in a very creative way."
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Friday 15 August 2008
The Verve's V Festival Appearances Shrouded In Mystery
The Verve's headlining visual aspect at this weekend's V Festival is shrouded in mystery today (August 13th) following reports of a new severance in the band.
According to a number of news outlets, guitar player Nick McCabe is struggling with the bands current workload and is �on the brink of walking out�.
He did a similar thing earlier the band's headlining one-armed bandit at the festival x years ago, leaving The Verve to find in a last minute replacement guitarist.
The claims follow reports that McCabe flew home separately undermentioned their show at Summer Sonic in Japan last weekend.
Last nighttime, the ring issued a statement denying that they were on the verge of cancelling their appearance atthe V Festival, which takes place in both Staffordshire and Chelmsford.
They said McCabe had simply suffered a finger combat injury and, wayward to reports, had non been section while in Japan.
Since their reformation last year, The Verve have headlined the Glastonbury Festival, T in the Park and release their new record album 'Forth' later this month.
Check out Gigwise's 20 Ones to Watch at the V Festival this weekend HERE.
The Verve's 2008 Comeback
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Thursday 7 August 2008
Third World
Artist: Third World
Genre(s):
Other
Discography:
Greatest Hits
Year: 1995
Tracks: 16
Third World is one and only of the longest-lived reggae bands of all meter, and 1 of Jamaica's virtually systematically popular carrefour over acts of the Apostles among
Friday 27 June 2008
'Frost/Nixon' kicking off London Film Festival
Ron Howard expected to be on hand for Oct. 15 screening
LONDON -- A journalist and a U.S. president will provide the opening-night drama at this year's BFI London Film Festival as "Frost/Nixon" kickstarts the event.
Organizers will roll out the red carpet for Ron Howard's big-screen adaptation of Peter Morgan's stage play Oct. 15.
Michael Sheen and Frank Langella reprise their West End and Broadway roles as journalist David Frost and President Richard Nixon in the film that LFF artistic director Sandra Hebron described as a "fascinating study of a unique moment in cultural and political life."
Kevin Bacon, Oliver Platt, Sam Rockwell, Rebecca Hall, Toby Jones and Matthew Macfadyen round out the cast in the movie, which centers on the 1977 televised David Frost and Richard Nixon interviews.
Those interviews attracted the largest audience for a news program in the history of American television, with more than 45 million viewers.
Howard and producer Brian Grazer, together with Working Title's Tim Bevan and Eric Fellner, are expected to be on hand to herald the movie's world premiere in London.
Universal Pictures will release the film in the U.K. in January.
The LFF is set for Oct. 15-30.
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Thursday 19 June 2008
Shakir Stewart joins Def Jam as exec vp
Succeeds former president Jay-Z
Def Jam Recordings has tapped Shakir Stewart as executive vp. Promoted from his post as senior vp A&R at Island Def Jam Music Group, Stewart succeeds former Def Jam president Shawn "Jay-Z" Carter.
In his new role, Stewart will retain his A&R responsibilities and report to IDJ chairman/CEO Antonio "L.A." Reid and to Steve Bartels, president and COO of the company on operational matters.
Promoted to IDJ's senior vp A&R in 2006, Stewart had previously served as VP/A&R at Def Jam since 2004. His signings during that period include hip-hop stars Rick Ross and Young Jeezy. Before that, Stewart held posts including senior vp creative and GM of Hitco Music Publishing, member of the executive A&R team at Arista Records and A&R consultant with LaFace Records.
Jay-Z spent three years as Def Jam's president before stepping down in late 2007. He recently inked a 360-degree deal with Live Nation.
Def Jam Recordings has tapped Shakir Stewart as executive vp. Promoted from his post as senior vp A&R at Island Def Jam Music Group, Stewart succeeds former Def Jam president Shawn "Jay-Z" Carter.
In his new role, Stewart will retain his A&R responsibilities and report to IDJ chairman/CEO Antonio "L.A." Reid and to Steve Bartels, president and COO of the company on operational matters.
Promoted to IDJ's senior vp A&R in 2006, Stewart had previously served as VP/A&R at Def Jam since 2004. His signings during that period include hip-hop stars Rick Ross and Young Jeezy. Before that, Stewart held posts including senior vp creative and GM of Hitco Music Publishing, member of the executive A&R team at Arista Records and A&R consultant with LaFace Records.
Jay-Z spent three years as Def Jam's president before stepping down in late 2007. He recently inked a 360-degree deal with Live Nation.
Saturday 14 June 2008
The Matrix - Weinsteins To Bring The Alchemist To Silver Screen
Paulo Coelho's bestselling novel The Alchemist is to be adapted for the screen by the Weinstein Company, it has been announced.
Laurence Fishburne, star of The Matrix, is to direct, produce and act in the project, while an Oscar-winning screenwriter is in negotiations with the Weinsteins to adapt Coelho's novel - which has sold more than 30 million copies worldwide - for the cinema.
Fishburne said the film was a "special project" and said the book's path to the screen would be "handled with the proper care it deserves".
He added: "I am looking forward to directing it, acting in it, and collaborating with Harvey Weinstein to produce a beautiful film that will do justice to Paulo's enormously successful novel."
The 1988 book tells of Santiago, a Spanish shepherd boy who travels through Africa in search of a magical treasure and has a fateful encounter with the titular alchemist.
Locations in Europe and the Middle East, such as Jordan and Abu Dhabi, are currently being scouted for the project while a casting search will begin in Spain and Latin America shortly for the boy most suited to taking the role of Santiago.
Harvey Weinstein, co-president of the Weinstein Company, said he would personally co-produce the project as bringing Coelho's "spiritual and moving" work to the screen was a long-term ambition.
And Coelho said he was "very happy" that his book would be filmed in the manner he intended.
"I hope the spirit and simplicity of my work will be preserved. I am excited my friend Laurence Fishburne and Harvey Weinstein will be working together," he added.
19/05/2008 10:58:27
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