�Takeda Pharmaceutical Company Limited (TOKYO:4502) and Affymax, Inc. (Nasdaq:AFFY) today announced their agreement to suspend co-development of Hematide� to treat chemotherapy-induced anemia and to focus all development efforts for Hematide� on the treatment of chronic kidney disease related anemia. Takeda and Affymax continue to be encouraged by the potential of bringing Hematide, a commodious, once monthly treatment alternative, to the millions of chronic kidney disease patients suffering from anemia and believe this represents a significant opportunity for the two companies.
Takeda has been conducting Phase I clinical studies of Hematide� for the treatment of chemotherapy-induced anemia in the U.S. and Japan. However, the companies have decided to suspend development of Hematide in oncology and not to enroll newfangled patients in the on-going Phase I clinical trial of the product in chemotherapy-induced anaemia given the uncertain regulative landscapes for
Thursday 4 September 2008
Monday 25 August 2008
Poetry reading is the new rock'n'roll
The mention of poetry readings has often been sufficiency to pull in a room before the reader has even had chance to clear his or her throat. Now, the Myspace generation is taking its poetry to stages at rock festivals that would normally be the preserve of seasoned performers such as John Cooper Clarke or John Hegley.
One of the rising stars is 22-year-old Laura Dockrill, a former Brit School prot�g�e. She has Glastonbury, Latitude and Summer Sundae festivals under her belt already and has supported Adele, Kate Nash and Martha Wainwright on hitch. Her poems posted on the Myspace website birth been listened to over 300,000 times. This weekend Ms Dockrill volition be playing in figurehead of hundreds of citizenry at the Reading Festival.
"I'm playing the Alternative Stage at Reading, which can be a minute worrying as it is known as having quite a a ill-famed rock crowd," said Dockrill. "I make had strong times before � regular with Kate Nash's hearing. I've had people shout out out: 'I didn't issue forth here to hear tap!' I wrote my first verse form at the age of six, simply I never really thought I would turn out doing it as a full-time career."
The poet, who has signed a major publication deal with HarperCollins for her first base book Mistakes in the Background, believes that performance poetry or spoken word of honor, as it is also called, is about to break into the mainstream.
"I definitely think it's release to get hold of off in the side by side few days. There's so many good artists out there like Scroobius Pip and Aisle16. They are really exciting."
Last week the final of the third annual Summer Poetry Slam competition took place at the Roundhouse in London. Poets cured between 13 and 21 performed in front of hundreds of other teenagers and a panel of judges, competing to be crowned Summer Slam poetry champion 2008.
BBC Radio, which features Bespoken Word on Radio 4, has added another slot in its roster for poetry on Colin Murray's Radio 1 show.
Graham Frost, the jehovah of Bespoken Word, aforesaid that a new generation had developed: "There is a new type of entertainment which is packing people in to the performances. It's performance verse with selfsame strong ethics. There's an empowering nature where offspring people from all different backgrounds are addressing issues such as knife law-breaking, media pressure, the credit crunch, suicides. We're now seeing brigham Young people using their brains in a very creative way."
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Friday 15 August 2008
The Verve's V Festival Appearances Shrouded In Mystery
The Verve's headlining visual aspect at this weekend's V Festival is shrouded in mystery today (August 13th) following reports of a new severance in the band.
According to a number of news outlets, guitar player Nick McCabe is struggling with the bands current workload and is �on the brink of walking out�.
He did a similar thing earlier the band's headlining one-armed bandit at the festival x years ago, leaving The Verve to find in a last minute replacement guitarist.
The claims follow reports that McCabe flew home separately undermentioned their show at Summer Sonic in Japan last weekend.
Last nighttime, the ring issued a statement denying that they were on the verge of cancelling their appearance atthe V Festival, which takes place in both Staffordshire and Chelmsford.
They said McCabe had simply suffered a finger combat injury and, wayward to reports, had non been section while in Japan.
Since their reformation last year, The Verve have headlined the Glastonbury Festival, T in the Park and release their new record album 'Forth' later this month.
Check out Gigwise's 20 Ones to Watch at the V Festival this weekend HERE.
The Verve's 2008 Comeback
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Thursday 7 August 2008
Third World
Artist: Third World
Genre(s):
Other
Discography:
Greatest Hits
Year: 1995
Tracks: 16
Third World is one and only of the longest-lived reggae bands of all meter, and 1 of Jamaica's virtually systematically popular carrefour over acts of the Apostles among
Friday 27 June 2008
'Frost/Nixon' kicking off London Film Festival
Ron Howard expected to be on hand for Oct. 15 screening
LONDON -- A journalist and a U.S. president will provide the opening-night drama at this year's BFI London Film Festival as "Frost/Nixon" kickstarts the event.
Organizers will roll out the red carpet for Ron Howard's big-screen adaptation of Peter Morgan's stage play Oct. 15.
Michael Sheen and Frank Langella reprise their West End and Broadway roles as journalist David Frost and President Richard Nixon in the film that LFF artistic director Sandra Hebron described as a "fascinating study of a unique moment in cultural and political life."
Kevin Bacon, Oliver Platt, Sam Rockwell, Rebecca Hall, Toby Jones and Matthew Macfadyen round out the cast in the movie, which centers on the 1977 televised David Frost and Richard Nixon interviews.
Those interviews attracted the largest audience for a news program in the history of American television, with more than 45 million viewers.
Howard and producer Brian Grazer, together with Working Title's Tim Bevan and Eric Fellner, are expected to be on hand to herald the movie's world premiere in London.
Universal Pictures will release the film in the U.K. in January.
The LFF is set for Oct. 15-30.
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Thursday 19 June 2008
Shakir Stewart joins Def Jam as exec vp
Succeeds former president Jay-Z
Def Jam Recordings has tapped Shakir Stewart as executive vp. Promoted from his post as senior vp A&R at Island Def Jam Music Group, Stewart succeeds former Def Jam president Shawn "Jay-Z" Carter.
In his new role, Stewart will retain his A&R responsibilities and report to IDJ chairman/CEO Antonio "L.A." Reid and to Steve Bartels, president and COO of the company on operational matters.
Promoted to IDJ's senior vp A&R in 2006, Stewart had previously served as VP/A&R at Def Jam since 2004. His signings during that period include hip-hop stars Rick Ross and Young Jeezy. Before that, Stewart held posts including senior vp creative and GM of Hitco Music Publishing, member of the executive A&R team at Arista Records and A&R consultant with LaFace Records.
Jay-Z spent three years as Def Jam's president before stepping down in late 2007. He recently inked a 360-degree deal with Live Nation.
Def Jam Recordings has tapped Shakir Stewart as executive vp. Promoted from his post as senior vp A&R at Island Def Jam Music Group, Stewart succeeds former Def Jam president Shawn "Jay-Z" Carter.
In his new role, Stewart will retain his A&R responsibilities and report to IDJ chairman/CEO Antonio "L.A." Reid and to Steve Bartels, president and COO of the company on operational matters.
Promoted to IDJ's senior vp A&R in 2006, Stewart had previously served as VP/A&R at Def Jam since 2004. His signings during that period include hip-hop stars Rick Ross and Young Jeezy. Before that, Stewart held posts including senior vp creative and GM of Hitco Music Publishing, member of the executive A&R team at Arista Records and A&R consultant with LaFace Records.
Jay-Z spent three years as Def Jam's president before stepping down in late 2007. He recently inked a 360-degree deal with Live Nation.
Saturday 14 June 2008
The Matrix - Weinsteins To Bring The Alchemist To Silver Screen
Paulo Coelho's bestselling novel The Alchemist is to be adapted for the screen by the Weinstein Company, it has been announced.
Laurence Fishburne, star of The Matrix, is to direct, produce and act in the project, while an Oscar-winning screenwriter is in negotiations with the Weinsteins to adapt Coelho's novel - which has sold more than 30 million copies worldwide - for the cinema.
Fishburne said the film was a "special project" and said the book's path to the screen would be "handled with the proper care it deserves".
He added: "I am looking forward to directing it, acting in it, and collaborating with Harvey Weinstein to produce a beautiful film that will do justice to Paulo's enormously successful novel."
The 1988 book tells of Santiago, a Spanish shepherd boy who travels through Africa in search of a magical treasure and has a fateful encounter with the titular alchemist.
Locations in Europe and the Middle East, such as Jordan and Abu Dhabi, are currently being scouted for the project while a casting search will begin in Spain and Latin America shortly for the boy most suited to taking the role of Santiago.
Harvey Weinstein, co-president of the Weinstein Company, said he would personally co-produce the project as bringing Coelho's "spiritual and moving" work to the screen was a long-term ambition.
And Coelho said he was "very happy" that his book would be filmed in the manner he intended.
"I hope the spirit and simplicity of my work will be preserved. I am excited my friend Laurence Fishburne and Harvey Weinstein will be working together," he added.
19/05/2008 10:58:27
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Sunday 8 June 2008
Winehouse visits clinic after video expos�
Troubled star Amy Winehouse visited a drugs clinic yesterday after she was caught on video apparently smoking crack cocaine, it was reported today.
The star is said to have visited a clinic in north-west London with her father for a two-hour appointment.
The visit comes as the Metropolitan Police confirmed it would investigate a video obtained by The Sun that appeared to show her inhaling fumes from a crack pipe, taking other drugs such as ecstasy and cocaine and admitting to downing six Valium.
The disturbing images were said to have been filmed during a party at Winehouse's east London home in the early hours of last Friday, hours before she attended a court hearing for husband Blake Fielder-Civil.
He is awaiting trial on charges of assault and conspiracy to pervert the course of justice.
The 24-year-old's father Mitch told The Sun: "Your video of Amy taking drugs may well be the best thing that has ever happened to her.
"For all the hurt and pain, it may finally be the thing to focus her mind and convince her to get the help she needs to quit for good."
Winehouse's spokesman told reporters the appointment at the clinic was a regular weekly session which formed part of her continuing treatment for drug addiction.
A Scotland Yard spokesman said: "Officers will be viewing the footage when we receive it from the media.
"We will then assess the footage to ascertain whether any action needs to be taken. As always we thank the media for their co-operation."
In The Sun's video the singer appears to be having a 19-minute drugs binge in which she snorts powdered ecstasy and cocaine before heading to her bedroom, where she inhales crack cocaine in front of her wedding photo.
Looking dishevelled and wearing a grubby black vest, she is left barely able to talk.
When friends ask her to go out with them, she is heard to reply: "I'd be useless to you because I've had about six Valium."
The star is said to have visited a clinic in north-west London with her father for a two-hour appointment.
The visit comes as the Metropolitan Police confirmed it would investigate a video obtained by The Sun that appeared to show her inhaling fumes from a crack pipe, taking other drugs such as ecstasy and cocaine and admitting to downing six Valium.
The disturbing images were said to have been filmed during a party at Winehouse's east London home in the early hours of last Friday, hours before she attended a court hearing for husband Blake Fielder-Civil.
He is awaiting trial on charges of assault and conspiracy to pervert the course of justice.
The 24-year-old's father Mitch told The Sun: "Your video of Amy taking drugs may well be the best thing that has ever happened to her.
"For all the hurt and pain, it may finally be the thing to focus her mind and convince her to get the help she needs to quit for good."
Winehouse's spokesman told reporters the appointment at the clinic was a regular weekly session which formed part of her continuing treatment for drug addiction.
A Scotland Yard spokesman said: "Officers will be viewing the footage when we receive it from the media.
"We will then assess the footage to ascertain whether any action needs to be taken. As always we thank the media for their co-operation."
In The Sun's video the singer appears to be having a 19-minute drugs binge in which she snorts powdered ecstasy and cocaine before heading to her bedroom, where she inhales crack cocaine in front of her wedding photo.
Looking dishevelled and wearing a grubby black vest, she is left barely able to talk.
When friends ask her to go out with them, she is heard to reply: "I'd be useless to you because I've had about six Valium."
Friday 30 May 2008
Jennifer Hudson album due in September
First single available for download in June
NEW YORK -- Academy Award-winning actress and former "American Idol" contestant Jennifer Hudson will release her debut album, a self-titled affair, in September via Arista Records. The first single, "Spotlight," will hit U.S. radio on June 9 and be available for sale via digital outlets the following day.
"Spotlight" was written by Ne-Yo, who co-produced along with Stargate. Additional contributors on the album include Timbaland, Robin Thicke, the Underdogs, Diane Warren and Christopher "Tricky" Stewart, among others.
"I think people will be pleasantly surprised, because it shows a side of my work that no one has heard before," Hudson said of the new album.
Hudson won the 2007 Academy Award for best supporting actress for her role as Effie White in "Dreamgirls." She next appears in the film adaptation of the HBO series "Sex and the City" and on its soundtrack, due May 27 via New Line, as well as "The Secret Life of Bees," which opens in the U.S. on Oct. 17.
NEW YORK -- Academy Award-winning actress and former "American Idol" contestant Jennifer Hudson will release her debut album, a self-titled affair, in September via Arista Records. The first single, "Spotlight," will hit U.S. radio on June 9 and be available for sale via digital outlets the following day.
"Spotlight" was written by Ne-Yo, who co-produced along with Stargate. Additional contributors on the album include Timbaland, Robin Thicke, the Underdogs, Diane Warren and Christopher "Tricky" Stewart, among others.
"I think people will be pleasantly surprised, because it shows a side of my work that no one has heard before," Hudson said of the new album.
Hudson won the 2007 Academy Award for best supporting actress for her role as Effie White in "Dreamgirls." She next appears in the film adaptation of the HBO series "Sex and the City" and on its soundtrack, due May 27 via New Line, as well as "The Secret Life of Bees," which opens in the U.S. on Oct. 17.
Tuesday 27 May 2008
Shwayze's Lazy Days Inspired By Malibu Party-Hopping With Cisco Adler: 'It's Like Summer In A Bottle'
From afar, Malibu, California, seems like a mystical place, a sun-splashed, paparazzi-cluttered playground for the rich and famous. And while Malibu is just that for some, real people live there too — hardworking Americans who're just trying to keep the lights on and food on the table. For much of his life, Aaron Smith, the self-professed "only black kid in Malibu" who goes by the stage name Shwayze, has been the latter, hailing from the city's Point Dume Club mobile-home park, where he'd lived with his grandparents.
But these days he's crashing on Cisco Adler's couch, and while he doesn't have his own Wikipedia page yet, all of that may soon change for backpack hip-hopper Shwayze. With a single ("Buzzin' ") that's generating radio spins nationwide, a video that's something of a rotation staple for "TRL," a stint on this summer's Warped Tour and a reality-TV series coming this summer from MTV, Shwayze's making the transition from nobody to hitmaker.
Considered a protégé of Adler (that Jonathan Davis-esque dude who's dated Mischa Barton and Lauren Conrad), Shwayze is set to release his debut album on July 15. Produced by Adler — who played most of the album's instruments, save for a guitar solo contributed by Jane's Addiction's Dave Navarro on the song "Flashlight" — in his home studio, Lazy Days was all but in the bag by the time Shwayze was signed to Jordan Schur's Suretone Records, and blends the artist's earliest rock influences with the rap and hip-hop ones that would come as he matured.
"I think it's really cool," Shwayze told MTV News recently of his music, which has been compared to Sublime. "It's like summer in a bottle. It's music that's indicative of this area — it's sunny, laid-back, summertime music, and it's something different than what's on the radio now. We made the record last summer, and it was sort of the blueprint of what we were doing. It had an 'Endless Summer' vibe to it."
The inspiration for the tunes, he confessed, came from the time he's spent party-hopping with Adler in the 'Bu, so most of the songs are about meeting girls, having fun and ... um ... meeting girls.
"We made the record on a whim, and we made it without a record label," Shwayze said during a spirited game of "street golf" — which involves stealing rocks from people's gardens — with Adler in his old 'hood. "And I think because of that, it came out natural and organic."
"I saw him at parties, and I was like, 'Damn, that dude's got some charisma, and I think he's got some talent — let's see if we can mold that into something special,' " Adler said. "And he started hounding me: 'Let's get in the studio.' We sort of looked at each other after we made a couple of songs, and we were like, 'Damn, this is kind of good.' "
In July, Shwayze's reality series, also called "Buzzin'," will chronicle the artist's journey from the streets of Malibu to signing a record deal. "It's about us rolling around, having fun, making music and trying to break an artist," he said.
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Heather Mills, Paul McCartney divorce finalized
Sir Paul McCartney’s divorce from Heather Mills was this morning finalized by a High Court judge in London.
Mr. Justice Bennett pronounced a decree nisi on the grounds that the couple have lived apart for two years.
Heather, 40, was awarded a $48.6m settlement from the former Beatle in March.
Neither Mills or McCartney were present at the hearing. They must now wait six weeks and one day before the decree is made absolute.
During the former couple’s High Court battle in March, Heather was criticized in the judgment for giving “inconsistent and inaccurate” evidence.
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Beckham gets new six-inch tattoo of Posh
David Beckham has pledged his love to wife Victoria by spending over €3,300 on a new tattoo.
The footballer's new design shows the Spice Girl posing as a naked angel - a copy of his favourite photo of his wife from a Brigitte Bardot-inspired shoot for Pop magazine almost four years ago.
The tattoo, inked onto his left arm, is Beckham's 11th. He already boasts designs bearing his wife and three sons' names.
A source close to the couple told the Mirror newspaper: "They are both thrilled with the result. It's been beautifully done. Victoria was flattered."
Beckham showed off his new tattoo during his visit to Brazil. The footballer is in the country to launch his third soccer academy.
The footballer's new design shows the Spice Girl posing as a naked angel - a copy of his favourite photo of his wife from a Brigitte Bardot-inspired shoot for Pop magazine almost four years ago.
The tattoo, inked onto his left arm, is Beckham's 11th. He already boasts designs bearing his wife and three sons' names.
A source close to the couple told the Mirror newspaper: "They are both thrilled with the result. It's been beautifully done. Victoria was flattered."
Beckham showed off his new tattoo during his visit to Brazil. The footballer is in the country to launch his third soccer academy.
Eva Mendes checks into rehab: reports
Hollywood star Eva Mendes has entered rehab to tackle substance-abuse problems, according to a report by People magazine.
The 33-year-old star of 'We Own the Night' is reported to have been undergoing treatment at Utah's Cirque Lodge centre for several weeks.
A representative for Mendes People's website: "Eva has been working hard for the past year and made a positive decision to take some much-needed time off to proactively attend to some personal issues that, while not critical, she felt deserved some outside professional support. Out of respect for Eva's privacy, we do not wish to discuss further details."
Last year Cirque Lodge was in the headlines after actress Lindsay Lohan checked into the facility following dual arrests for drink-driving.
Mendes is one of the best known Latino actresses in Hollywood, having risen to prominence after landing a role with Denzel Washington in 2001 hit 'Training Day'.
Later this year she will appear in a remake of 'The Women', starring alongside Meg Ryan, Annette Bening, Debra Messing, Jada Pinkett-Smith and Bette Midler.
The 33-year-old star of 'We Own the Night' is reported to have been undergoing treatment at Utah's Cirque Lodge centre for several weeks.
A representative for Mendes People's website: "Eva has been working hard for the past year and made a positive decision to take some much-needed time off to proactively attend to some personal issues that, while not critical, she felt deserved some outside professional support. Out of respect for Eva's privacy, we do not wish to discuss further details."
Last year Cirque Lodge was in the headlines after actress Lindsay Lohan checked into the facility following dual arrests for drink-driving.
Mendes is one of the best known Latino actresses in Hollywood, having risen to prominence after landing a role with Denzel Washington in 2001 hit 'Training Day'.
Later this year she will appear in a remake of 'The Women', starring alongside Meg Ryan, Annette Bening, Debra Messing, Jada Pinkett-Smith and Bette Midler.
Hernandez voted off American Idol
David Hernandez has become the latest contestant to be voted off 'American Idol'.
Hernandez was placed in the bottom three with Syesha Mercado and Kristy Lee Cook and viewers voted to eliminate the 24-year-old.
Hernandez had sung 'I Saw Her Standing There' on the Lennon-McCartney-themed episode.
Commenting after his elimination, he said: "Honestly, things happen for a reason. We all have a plan, and on top of that you'll see me at the top. This isn't it for me."
Hernandez was the subject of controversy last week following media reports that he had worked as a stripper.
Hernandez was placed in the bottom three with Syesha Mercado and Kristy Lee Cook and viewers voted to eliminate the 24-year-old.
Hernandez had sung 'I Saw Her Standing There' on the Lennon-McCartney-themed episode.
Commenting after his elimination, he said: "Honestly, things happen for a reason. We all have a plan, and on top of that you'll see me at the top. This isn't it for me."
Hernandez was the subject of controversy last week following media reports that he had worked as a stripper.
Miller amongst BAFTA rising star nominees
Sienna Miller has been nominated for this year's Rising Star award at the BAFTAs.
The actress, who recently appeared in 'Stardust', is amongst two British stars nominated for the award, which is voted for by the public. Sam Riley, the star of Joy Division biopic 'Control', is the other British nominee.
They're joined in the category by Ellen Page, Shia LaBeouf and 'Lust, Caution' star Tang Wei for the prize.
The category was established in honour of late casting director Mary Selway, who died in 2004, with Scottish actor James McAvoy picking up the inaugural award.
'Casino Royale' star Eva Green, who won the award last year, announced the nominees saying: "This year's five nominees are all actors who have really stood out in their work and I'm sure we'll see a lot more of them throughout 2008."
The winner will be announced at the official BAFTA ceremony on 10 February.
The actress, who recently appeared in 'Stardust', is amongst two British stars nominated for the award, which is voted for by the public. Sam Riley, the star of Joy Division biopic 'Control', is the other British nominee.
They're joined in the category by Ellen Page, Shia LaBeouf and 'Lust, Caution' star Tang Wei for the prize.
The category was established in honour of late casting director Mary Selway, who died in 2004, with Scottish actor James McAvoy picking up the inaugural award.
'Casino Royale' star Eva Green, who won the award last year, announced the nominees saying: "This year's five nominees are all actors who have really stood out in their work and I'm sure we'll see a lot more of them throughout 2008."
The winner will be announced at the official BAFTA ceremony on 10 February.
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